11:30-14:00 |
Registration and posters set-up |
14:00-14:30 |
Welcome and Opening of the Congress |
14:30-16:00 |
Session 1: Epigenetics Chairs: Pier Giuseppe Pelicci (Milan) Davide Corona (Palermo) Inheritance of epigenetic memory through ncRNAs Gioacchino Natoli (Milan) Macrophage specialization and plasticity: what can we learn from genomic analyses Henk Stunnenberg (Nijmegen, Netherlands) The epigenome of groundstate mouse embryonic stem cells |
16:00-17:00 |
![]() Plenary Lecture Pietro De Camilli (New Haven, CT, USA) Phosphoinositide signaling in the control of membrane dynamics and interactions |
17:00-17:30 |
Coffee break |
17:30-18:30 |
![]() AIRC Lecture Fiona Watt (London, UK) Regulation of epidermal stem cell fate by intrinsic and extrinsic mechanisms |
18:30-20:30 |
Poster session A and buffet dinner |
9:00-10:30 |
Session 2: Autophagy Chairs: Antonio Musarò (Rome) Francesco Cecconi (Rome) Autophagy and cancer: don't mess with the cell cycle! Ana Maria Cuervo (Bronx, NY, USA) Selective autophagy: the "in" and "out" of the lysosome Marco Sandri (Padua) Autophagy and the quality control of proteins and mitochondria |
10:30-11:30 |
![]() Plenary Lecture Luigi Naldini (Milan) Genetic engineering of human hematopoiesis for treating inherited diseases and cancer |
11:30-12:00 |
Coffee break |
12:00-13:30 |
Session 3: Cell migration and invasion Chairs: Elisabetta Dejana (Milan) Matthieu Piel (Paris, France) Cell migration under confinement: pushing off the walls and squeezing the nucleus Giorgio Scita (Milan) Endocytic networks in the control of the plasticity of tumor dissemination Livio Trusolino (Turin) Precision medicine in metastatic colorectal cancer: opportunities and challenges |
13:30-14:30 |
Lunch break |
14:30-15:30 |
![]() FUV Lecture Daniel St Johnston (Cambridge, UK) Epithelial polarity and spindle orientation |
15:30-16:30 |
![]() Plenary Lecture Margaret Buckingham (Paris, France) Regulation of muscle stem cell fate: progression into the myogenic programme during muscle formation in the embryo and during muscle regeneration in the adult |
16:30-17:00 |
Coffee break |
17:00-18:30 |
Session 4: Organelle homeostasis and disease Chair: Nica Borgese (Milan) Christian Frezza (Cambridge, UK) The role of altered metabolism in tumorigenesis Eelco van Anken (Milan) Endoplasmic reticulum stress signaling sites in sight Rosario Rizzuto (Padua) Molecular composition and physiological role of the mitochondrial calcium uniporter |
18:30-20:30 |
Poster session B and buffet dinner |
9:00-10:30 |
Session 5: Cellular mechanisms of ageing Chairs: Marco Crescenzi (Rome) Yves Barral (Zurich, Switzerland) Molecular mechanisms for the asymmetric segregation of age during cell division Luigi Fontana (St. Louis, MO, USA / Salerno) Metabolic and molecular effects of dietary restriction in humans Natascia Ventura (Rome) Mitochondrial-stress control of longevity: C. elegans as a powerful genetic model organism |
10:30-11:00 |
Coffee break |
11:00-12:00 |
![]() Plenary Lecture Joachim Wittbrodt (Heidelberg, Germany) Lineage restriction and multipotency of retinal stem cells |
12:00-12:10 |
![]() Closing Remarks Francesco Clementi (Milan) 30 years of ABCD |
12:10-14:30 |
Lunch break |
14:30-18:00 |
Special Interest Groups • Parallel Sessions 1. Mechanisms of signal transduction |
|
18:30-19:30 |
ABCD Assembly |
20:30 |
Social dinner |
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Topic 1: Mechanisms of signal transduction
Topic 2: Membrane trafficking and organelle biogenesis
P1.1 Filippo Acconcia (Rome) Role of endocytic internalization routes in 17beta-estradiol-induced estrogen receptor alpha signalling |
P1.2 Elena Adinolfi (Ferrara) The P2X7 receptor: from ion channel to oncogene |
P1.3 Veronica Algisi (Milan) Molecular characterization of clathrin-dependent EGFR endocytosis unveils distinct internalization mechanisms that couple with different signalling outputs |
P1.4 Francesca Amoroso (Ferrara) P2X7 receptor as key modulator of PI3K/HIF1α/GSK3β metabolic pathway in neuroblastoma |
P1.5 Chiara Amoruso (Naples) The anti-invasive activity of the glycerophosphoinositols involves the phosphatase Shp1 |
P1.6 Flora Ascione (Naples) Investigation of cell dynamics by in vitro Time Lapse Microscopy |
P1.7 Giuseppa Augello (Palermo) VO-OHpic, a novel PTEN inhibitor, induces senescence and sensitivity to PI3K/Akt/mTOR inhibitors in human liver cancer cells characterized by low expression of PTEN |
P1.8 Daniele Avitabile (Rome) Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene |
P1.9 Anush Bakunts (Milan) Selective interaction of endoplasmic reticulum stress sensor IRE1 with client proteins in vitro |
P1.10 Chiara Battistini (Candiolo) Rhomboid proteases and cancer progression: the role of RHBDL2 |
P1.11 Diana Bellavia (Roma) Notch3 and Jagged1 cis-interaction reinforces Notch signaling and sustains T-ALL development |
P1.12 Jessika Bertacchini (Modena) Adaptive capabilities of the PI3K/Akt/mTOR axis in Acute Myeloid Leukemia revealed by pathways selective inhibition and phosphoproteome analysis |
P1.13 Giuseppina Bozzuto (Rome) A comparative study of migratory and invasive behaviours of tumor cells |
P1.14 Alessandra Braga (Padua) Role of PKCzeta on skeletal muscle homeostasis |
P1.15 Marina Capece (Ferrara) P2X7 contemporarily impacts melanoma growth and anti–melanoma defense |
P1.16 Lucia Casoli (Milano) Role of Myc in TGFβ-induced EMT |
P1.17 Luisa Castagnoli (Rome) Establishing the logic network underlying the anti-cancer activity of metformin: a systems biology approach |
P1.18 Daniela Cimino (Torino) microRNA sponges as therapeutic tools to affect cancer progression |
P1.19 Olivia Crociani (Firenze) Molecular and functional characterization of the hERG1/b1 integrin complex in tumor cells |
P1.20 Marcello Delfini (Milan) Molecular mechanisms of beta arrestin2 dependent chemokine induced leukocyte extravasation |
P1.21 Augusta Di Savino (Turin) Morgana is a new oncosuppressor in chronic myeloid leukemia |
P1.22 Luca Drusian (Milano) The role of mTORC1 and TCA cycle in renal cyst formation and transformation |
P1.23 Elisa Duregotti (Padova) Role of peripheral schwann cells in the regeneration of degenerated nerve terminals at the neuromuscular junction |
P1.24 Emanuela Fanigliulo (Siena) The Rai adaptor protein in Th17 cell differentiation, effector function and in the pathogenesis of multiple sclerosis |
P1.25 Annarita Favia (ROMA) Targeting of NAADP/Two Pore Channels (TPC2) signaling inhibits VEGF-induced angiogenesis |
P1.26 Federica Fusella (Turin) Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway |
P1.27 Simone Gallo (Milan) Regulation of protein synthesis by eIF6 modulators RACK1 and EFTUD1 |
P1.28 Gaia Gherardi (Padua) Mitochondrial calcium signalling in the control of skeletal muscle homeostasis |
P1.29 Anna Gorrasi (Fisciano (Sa)) The urokinase receptor associates to fMLF chemotaxis receptors |
P1.30 Francis Mungathia Kobia (Milano) Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling |
P1.31 Anna Li Santi (Fisciano) The urokinase receptor takes control of cell migration through a mechanism involving integrins and fMLF receptors |
P1.32 Caterina Lucano (Milan) A novel role of the endocytic adaptor proteins Eps15 and Eps15L1 in the regulation of Notch signaling |
P1.33 Roberta Melchionna (Rome) hMENA splicing is critical in the lost of epithelial integrity and cell invasiveness in pancreatic cancer |
P1.34 Agnese Molinari (Rome) Study of migratory and invasive behaviour of glioblastoma cancer stem cells |
P1.35 Stefania Oliveto (Milan) eIF6 hyperphosphorylation and activity in cancer |
P1.36 Maurizio Onisto (Padua) Heparanase: analysis of its contribution in the epithelial to mesenchymal transition process and its validation as pharmacological target |
P1.37 Veronica Oropallo (Rome) ATM protein kinase promotes HER2-dependent tumorigenesis |
P1.38 Andrea Orsi (Milan) Dynamics and ultrastructure of ER stress sensing |
P1.39 Angela Paggio (Padua) Control of mitochondria morphology by CCDC51 |
P1.40 Tito Panciera (Padua) Role of YAP/TAZ in mechanotransduction exploring the mechanics of contact inhibition |
P1.41 Elisa Penna (Padua) Control of organelle morphology by mitochondrial calcium concentration |
P1.42 Francesca Pescatore (Padua) The FOXO signature in muscle wasting. Definition of the gene network that controls protein degradation |
P1.43 Valeria Pesiri (Rome) Non covalent ubiquitin binding to the estrogen receptor alpha controls its monoubiquitination and 17β-estradiol-induced cell proliferation |
P1.44 Pier Giorgio Petronini (Parma) PI3K gene alterations as predictive factor for the use of PI3K/mTOR inhibitors in NSCLC cell lines |
P1.45 Tommaso Pozzobon (Padua) Pro-angiogenic activity of TpF1 produced by Treponema pallidum |
P1.46 Monica Raimo (Torino) microRNA-146a controls melanoma via a novel pathway |
P1.47 Danilo Ranieri (Rome) Nuclear redox imbalance affects circadian clock synchronization in human keratinocytes |
P1.48 Alessandro Rimessi (Ferrara) H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling |
P1.49 Francesca Rocchio (Novara) Role of deubiquitinating enzyme in the DNA damage response activation |
P1.50 Matteo Rossi (Siena) Expression of MAPK15 in normal testis and in testicular cancer |
P1.51 Alessandra Tesi (Milano) Genome interactions and gene regulation by myc in B cells activation |
P1.52 Emiliana Tognon (Milano) Regulation of the v-ATPase expression during developmental signaling |
P1.53 Anna Tosatto (Padua) Mitochondrial calcium regulation in triple negative breast cancer |
P1.54 Eleonora Valentini (Milan) Studying the ubiquitin E3-ligase Rabex-5 in the context of Ras regulation |
P1.55 Denis Vecellio Reane (Padua) Identification of new mitochondrial calcium uniporter regulators |
P1.56 Lisette Verhoef (Milan) RTN3 mediates ubiquitin-dependent, clathrin-independent EGFR internalization |
P1.57 Rosella Visintin (Milan) Regulation of anaphase progression by the Cdc14 phosphatase and Cdc5 kinase |
P2.1 Victor Alfred (Milano) A deficiency screen to identify genetic interactors of ESCRT-II subunit, vps25 in Drosophila melanogaster |
P2.2 Giuseppina Amodio (Fisciano) Proteomic identification of Sec23a post-translational modifications |
P2.3 Tiziana Anelli (Milan) ERp44, a multitask protein integrating protein folding and transport, redox homeostasis and Ca2+ signaling |
P2.4 Manuela Antoniel (Padova) Modulation of CyPD-FoF1ATP synthase interactions by pH: role of histidine protonation |
P2.5 Paola Bagnato (Genoa) Role of ErbB1 in Trastuzumab-induced ErbB2 signaling and internalization |
P2.6 Francesca Belleudi (Rome) Autophagy in human keratinocytes: sequential involvement of KGF in autophagosome assembly and turnover |
P2.7 Matteo Biancospino (Milan) Ubiquitin and Clathrin are alternative binders of Myosin VI |
P2.8 Nica Borgese (Milan) Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor |
P2.9 Cecilia Bucci (Lecce) Rab7a interacts with intermediate filament proteins |
P2.10 Carlo Campa (Torino) Identification of novel RAB11 activators |
P2.11 Patrizia Cassella (Milan) Investigation of the targeting mechanism of a spontaneously inserting tail-anchored protein |
P2.12 Alessia Castagnino (Genoa) ErbB2 membrane redistribution induced by Trastuzumab in SK-BR-3 cells |
P2.13 Saula Checquolo (Rome) Role of Pin1 prolyl-isomerase in notch3-dependent leukemia |
P2.14 Sara Colombo (Milan) TRC40-dependent insertion of tail-anchored proteins into proteoliposomes reconstituted from rat liver microsomal detergent extracts |
P2.15 Salvatore Corallino (Milan) Identification of molecular determinants of tumor invasive programs by RNAi-based phenotypic screening |
P2.16 Katia Cortese (Genoa) The HSP90 inhibitor Geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments |
P2.17 Tiziana Daniele (Milan) Mitochondria establish physical contacts with melanosomes and provide ATP required for their biogenesis |
P2.18 Maria De Luca (Lecce) Regulation of the G1 subunit of the V-ATPase proton pump by RILP |
P2.19 Donatella Galgano (Siena) IFT20 interacts with endosomal RABS to control TCR recycling and immune synapse assembly in concert with IFT52 and IFT57 |
P2.20 Corrado Garbi (Naples) Rac1 inhibition affects polarity and modulates E-cadherin dynamics |
P2.21 Paola Genevini (Milan) Structure, biogenesis, and clearance of ER-derived inclusions generated by the ALS-linked mutant of VAPB |
P2.22 Letizia Lanzetti (Candiolo) RN-tre controls focal adhesion turnover and cell migration |
P2.23 Giulia Mana (Candiolo) Conformation and subcellular localization of ligand-bound/active β1 integrins control their endocytosis |
P2.24 Paola Marighetti (Milan) Role of the CDC42-interacting protein 4 (CIP4) in cell cohesion and tumor dissemination |
P2.25 Giulia Masi (Siena) p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics |
P2.26 Anna Mattioni (Rome) The interaction between the E3-ligase RNF11 and the Ankrd 13 protein family evokes new insight into RNF11 cellular dynamics |
P2.27 Lucio Nitsch (Naples) A corepressor gene mapping to chromosome 21 affects mitochondrial function in Down syndrome cells |
P2.28 Simona Paladino (Naples) Lipid rafts regulate signalling and trafficking of p75NTR in thyroid cells |
P2.29 Vito Pesce (Bari) Mitochondrial biogenesis, mitochondrial dynamics, mitochondrial antioxidant defenses and the mtDNA4834 deletion level in cerebral hemispheres and cerebellum of old rat chronically treated with acetyl-L-carnitine |
P2.30 Antonella Ragnini-Wilson (Santa Maria Imbaro (Ch)) Human orthologues of yeast Mlc1 are required for HeLa cell cytokinesis |
P2.31 Irene Righetto (Padua) Preliminary characterization of human VAMP7b isoform |
P2.32 Paola Rusmini (Milan) The role of small heat shock proteins HSPB2 and HSPB8 in spinal and bulbar muscular atrophy |
P2.33 Sara Sannino (Milan) pH-dependent regulation of ERp44 in the Early Secretory Compartment |
P2.34 Guido Serini (Candiolo) The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling |
P2.35 Caterina Tezze (Padua) The mitochondria shaping protein OPA1 is required for muscle growth and animal survival |
P2.36 Lorena Urbanelli (Perugia) The Human Lysosomal Gene Database: an insight into lysosomal system regulation |
P2.37 Caterina Valetti (Genoa) Russell bodies as a model of ER storage diseases |
P2.38 Mattia Vicario (Padua) A novel prion protein-tyrosine hydroxylase interaction |
P2.39 Giulia Viviani (Udine) The MEF2-HDAC class IIa axis and the control in breast epithelial morphogenesis |
P2.40 Francesca Zappa (Naples) CLIC1 is involved in membrane trafficking along the secretory pathway |
Topic 3: Stem cells, development and regenerative medicine
Topic 4: Cell stress: survival and apoptosis
P3.1 Lara Albania (Padua) Involvement of human VAMP7 splice isoforms in neuronal development |
P3.2 Blanca Alvarez Moya (Milan) Global proteomic profiling of asymmetry/cell fate determinants (“asymmetrome”) in mammary stem cells |
P3.3 Marco Annoni (Saronno) Integrating regenerative medicine and person-centred medicine: lessons and directions from the recent search for biomarkers of placebo response |
P3.4 Maria Grazia Berardinelli (Rome) Role of IL-6 in skeletal muscle growth and atrophy |
P3.5 Federico Boem (Milano) What is a gene? The thin red line of molecular biology |
P3.6 Maria Caruso (Rome) RSPO1/LGR4 system is expressed during mouse ovary development and influences germ cell meiotic process |
P3.7 Luca Chiapperino (Milan) Empowering patients, consuming health: the bio-objectification of patienthood in contemporary healthcare |
P3.8 Paola Contavalli (Rome) Cripto-1 controls dynamic stemness states in human colon cancer cells |
P3.9 Carolina D'Alesio (Milan) Identification of new druggable genes involved in breast tumorigenesis by means of a mouse model of mammary carcinoma |
P3.10 Maria Laura De Angelis (Rome) Cetuximab effect on colon cancer stem cells (cCSCs) |
P3.11 Fabiana Geraci (Palermo) Hsp70 and NFkB are involved in mouse mesoangioblast stem cells migration |
P3.12 Paola Grimaldi (Rome) TRPV1 receptor promotes neuronal differentiation of wild type and Spinal Muscular Atrophy neural stem cells |
P3.13 Carol Imbriano (Modena) A specific role for the splice variants of the transcription factor NF-Y in modulating the transcriptional activity of the myogenic program |
P3.14 Valeria Lucci (Naples) Dysregulation of PAX8 expression by miRNAs in ovarian cancer cells |
P3.15 Anna Maria Lustri (Roma) GDNF regulation of VASP expression levels in spermatogonial stem/progenitor cells |
P3.16 Simona Martinotti (Alessandria) In vitro mechanisms of honey-driven wound healing |
P3.17 Caterina Missero (Naples) Mutant p63 leads to focal skin lesions and a systemic immune system disorder in a conditional AEC mouse model |
P3.18 Susanna Molinari (Modena) Regulation of Mef2c activity by alternative splicing in zebrafish muscle development |
P3.19 Francesca Montani (Milan) Revealing the complexity of cancer associated small non-coding RNAs by Next Generation Sequencing (NGS) and low-density array |
P3.20 Simona Monterisi (Milano) HOXB7 and lung cancer: biological relevance of a homeobox gene in cancer progression |
P3.21 Deborah Pajalunga (Rome) Limited DNA replication in reactivated postmitotic cells: the role of the deoxyribonucleoside triphosphate pool |
P3.22 Rani Pallavi (Milan) Anti-tumor effect of caloric restriction via regulation of stem cell function |
P3.23 Eduardo Patriarca (Naples) L-proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation |
P3.24 Virginia Sanchini (Milan) From theory to practice. Towards the fulfilment of trusted based consent in research biobanks |
P3.25 Andrea Scelfo (Milan) Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancers fidelity |
P3.26 Marianna Sciortino (Turin) Identification of p130Cas/ErbB2 dependent invasive signatures in transformed mammary epithelial cells |
P3.27 Daniela Tosoni (Milano) The Numb/p53 circuitry couples the control of replicative asymmetry and tumour suppression in normal and cancer mammary stem cells |
P3.28 Cecilia Valvo (Rome) Development of new monoclonal antibodies targeting colon cancer stem cells |
P3.29 Alessandra Micaela Villa (Milan) Monoclonal antibodies from phage display libraries: new tools for the study of breast cancer stem cells |
P3.30 Sergio Visentin (Rome) Oscillatory Ca2+ waves, mitochondria, and nuclear receptors in the differentiation of oligodendrocytes |
P4.1 Francesca Aredia (Pavia) Activation of multiple death paradigms under cellular stress conditions |
P4.2 Michela Battistelli (Urbino) Melatonin, Hydroxytyrosol and other antioxidants prevent UVB -induced cell death in keratinocytes |
P4.3 Loredana Biancolillo (Rome) Role of the oncosuppressor HIPK2 in cytokinesis |
P4.4 Massimo Bonora (Ferrara) P53 controls calcium dependent cell death from the endoplasmic reticulum side |
P4.5 Liana Bosco (Palermo) A relationship between human sperm morphology and DNA fragmentation in infertile patients |
P4.6 Viola Calabrò (Naples) Cooperation between YB-1 and ΔNp63α in the control of cell proliferation and survival |
P4.7 Mariacristina Capizzi (Rome) The role of hsa-miR-7 and hsa-miR-9 in post- transcriptional regulation of AMBRA1The role of hsa-miR-7 and hsa-miR-9 in post- transcriptional regulation of AMBRA1 |
P4.8 Michela Carraro (Padova) Properties of the permeability transition pore of yeast mitochondria |
P4.9 Roberto Chiarelli (Palermo) The role of autophagy during the oogenesis of Paracentrotus lividus sea urchin |
P4.10 Martina Chrisam (Padua) Reactivation of autophagy by spermidine ameliorates the dystrophic phenotype of collagen VI null mice |
P4.11 Lucia Cicchillitti (Rome) Identification of a novel NF-Y protein partner: characterization of NF-YA/Lamin A nuclear complex |
P4.12 Marta Coccia (Roma) HSF1-mediated induction of AIRAP expression by 15-deoxy-Δ12,14-prostaglandin J2: an effect independent of Nrf-2 |
P4.13 Ivan Colaluca (milano) Structure/function analysis of the Numb/Hdm2/p53 circuitry in the perspective of therapeutic applications in cancer |
P4.14 Anna Comel (Trieste) Dissecting the tumor suppressor activity of the bromodomain containing protein BRD7 |
P4.15 Antonella Cusimano (Palermo) Antitumor activity of the novel small molecule Akt inhibitor SC66 in hepatocellular carcinoma cells |
P4.16 Alba D'Alessandro (Fisciano) N6-isopentenyladenosine triggers anti-glioma innate immune response through induction of ULBP2 in a p53-dependent manner |
P4.17 Luisa De Latouliere (Rome) Regulation of human MENA expression by NF-Y transcription factor |
P4.18 Luisa De Martino (Napoli) The role of sirtuins in cytopathic bovine viral diarrhoea virus-infected epithelial bovine cells |
P4.19 Gabriella De Vita (Naples) Thyroid cancer susceptibility gene foxe1 promotes cell motility and is required for the survival of adult thyroid cells |
P4.20 Tina Di Palma (Naples) Pax8 has a critical role in epithelial cell differentiation, survival and proliferation |
P4.21 Virginia Di Paolo (ROMA) Effects of PACAP and VIP on human ovarian cancer cell lines |
P4.22 Giuliana Di Rocco (Rome) Depletion of HIPK2 full-length protein preserving the ΔE8 isoform triggers apoptosis in colon cancer stem cells in vitro and in vivo |
P4.23 Maria Rita Emma (Palermo) Nupr1/p8 expression in human liver cancer cells: a possible role in controlling cell growth and sensitivity to drug treatment |
P4.24 Emmanuela Falcone (Rome) Crosstalk between mutp53 and NF-Y in the regulation of EMT |
P4.25 Maurizio Fanciulli (Rome) Che-1 induces Deptor expression in response to cellular stress sustaining autophagy and multiple myeloma growth |
P4.26 Francesca Ferranti (Rome) Morphological modifications induced by microgravity on TCam-2 seminoma cells |
P4.27 Filomena Fiorito (Napoli) 2,3,7,8-Tetrachlorodibenzo-p-dioxin influences PI3K/Akt, MAPKs, and mTORC pathways during Bovine herpesvirus 1 infection in MDBK cells |
P4.28 Francesca Garibaldi (Rome) MicroRNA regulation by mutant p53 oncoprotein in colon cancer |
P4.29 Stefano Garofalo (Rome) Effect of environmental enrichment on glioblasoma invasion |
P4.30 Veronica Granatiero (Padua) The role of mitochondrial calcium uniporter in neurodegeneration |
P4.31 Girolama La Mantia (Naples) The p14ARF tumor suppressor mediates cellular spreading through a Focal Adhesion Kinase dependent mechanism |
P4.32 Federica Maccarinelli (Brescia) Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity |
P4.33 Francesca Mancini (Roma) DNA damage induces early p53-mediated repression of anti-apoptotic molecules, which requires MDM4/HIPK2 integration |
P4.34 Chiara Martino (Palermo) Lack of magnesium causes stress response and skeleton defects in Arbacia lixula sea urchin embryos |
P4.35 Laura Monteonofrio (Rome) Characterization of the extra-chromosomal activity of histone H2B at the midbody |
P4.36 Alice Nardin (Padova) Parkin translocation is triggered by its dephosporylation by Calcineurin |
P4.37 Ivan Orlandi (Milano) Ethanol and acetate metabolism negatively affects yeast chronological aging |
P4.38 Veronica Orlandi (Padua) Analysis of the bioenergetic role played by mitochondrial chaperones and kinases in B-cell chronic lymphocytic leukemia (B-CLL) cells |
P4.39 Laura Ottaviani (Parma) Human oligodendroglioma cells are sensitive to glutamine deprivation induced by L-Asparaginase |
P4.40 Angelo Poletti (Milan) Inhibition of ATPase activity of dynein reduce aggregates of misfolded proteins in motoneuron disease |
P4.41 Maria Ragusa (Palermo) Combined effect of cadmium and sulfonamides on sea urchin development |
P4.42 Cristina Miazzi (Padova) The deoxynucleoside triphosphohydrolase SAMHD1 is a new catabolic regulator of DNA precursors in mammalian cells |
P4.43 Elia Ranzato (Alessandria) Demonstration of active nutrient/drug synergistic combination as a potential treatment for malignant pleural mesothelioma |
P4.44 Anna Riccio (Rome) The proteasome inhibitor bortezomib is a potent inducer of zinc-finger AN1-type domain-2a gene expression: implication of HSF1/HSF2 heterocomplexes in human endothelial cells |
P4.45 Roberta Russo (Palermo) Early and late responsive genes affected by UVB radiation in sea urchin embryos |
P4.46 Amal Saadeldin (Milan) Prosurvival mcl-1 and mtor contribute to sunitinib resistance |
P4.47 Michele Sallese (Santa Maria Imbaro (Ch)) The Golgi-localized KDEL receptor controls the extracellular matrix degradation |
P4.48 Sara Salucci (Urbino) Melatonin role in the prevention of skeletal myoblast cell death |
P4.49 Dijana Samardžić (Padova) The role of mitochondria-shaping protein Opa1 in the OxPhos subset of diffuse large B cell lymphoma |
P4.50 Angelo Taglialatela (Milan) CDK12 is a novel oncogene with clinical and pathogenetical relevance in breast cancer |
P4.51 Rosaria Tinnirello (Palermo) Cell clone selected from mab stem cells is more resistant to oxidative stress and retain some ability that could be useful for cell therapy |
P4.52 Claudia Tonelli (Milan) Genome-wide analysis of p53-dependent transcriptional programs in tumor suppression |
P4.53 Daniela Trisciuoglio (Rome) Histone deacetylase inhibition leads to enhanced sensitization to pemetrexed via induction of apoptosis and autophagy in non–small cell lung tumor models |
P4.54 Milena Vitale (Milan) IgM heavy chain µ as physiological stimulus for UPR activation |
P4.55 Masa Ždralević (Bari) Mitochondrial retrograde pathway is involved in yeast acetic acid-induced programmed cell death resistance |
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Antonio Musarò (Chair)
Fiorella Altruda
Paolo Bernardi
Nica Borgese
Marco Crescenzi
Antonella de Matteis
Elisabetta Dejana
Pier Paolo Di Fiore
Alfredo Fusco
Luigi Naldini
Pier Giuseppe Pelicci
Claudio Sette
Carlo Tacchetti
Bronislava Matoskova
Emanuela Orlando
Paolo Pinton
Stella Zannini